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Protein stickiness, rather than number of functional protein-protein interactions, predicts expression noise and plasticity in yeast

BACKGROUND: A hub protein is one that interacts with many functional partners. The annotation of hub proteins, or more generally the protein-protein interaction “degree” of each gene, requires quality genome-wide data. Data obtained using yeast two-hybrid methods contain many false positive interact...

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Bibliografske podrobnosti
Main Authors: Brettner, Leandra M, Masel, Joanna
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527306/
https://ncbi.nlm.nih.gov/pubmed/23017156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-128
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