Growth Inhibition by Acycloguanosine of Herpesviruses Isolated from Human Infections

Inhibition by acycloguanosine (ACG) of plaque formation by harpes simplex virus types 1 and 2 (HSV-1 and HSV-2), varicella-zoster virus, and cytomegalovirus was studied. Seventeen clinical isolates of HSV-1 were inhibited by ACG at a mean 50% inhibitory dose (ID(50)) of 0.15 ± 0.09 μM. The mean ID(5...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Crumpacker, Clyde S., Schnipper, Lowell E., Zaia, John A., Levin, Myron J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1979
Soggetti:	Pharmacology and Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352730/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/230783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.5.642
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