Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae

BACKGROUND: Sesquiterpenes are a class of natural products with a diverse range of attractive industrial proprieties. Due to economic difficulties of sesquiterpene production via extraction from plants or chemical synthesis there is interest in developing alternative and cost efficient bioprocesses....

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Main Authors: Scalcinati, Gionata, Partow, Siavash, Siewers, Verena, Schalk, Michel, Daviet, Laurent, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527295/
https://ncbi.nlm.nih.gov/pubmed/22938570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-117
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