Effect of Clavulanic Acid on the In Vitro Synergism Between Carbenicillin and Gentamicin Against Serratia marcescens

Clavulanic acid, a potent β-lactamase inhibitor, reduced the minimum inhibitory concentrations of carbenicillin for 13 of 15 clinical isolates of Serratia marcescens by at least eightfold. The combination of clavulanic acid and carbenicillin also exhibited synergistic activity with gentamicin agains...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Sirisanthana, Thira, Lerner, Stephen A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1979
Fag:	Physiological Effects and Microbial Susceptibility
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/380465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.4.630
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