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Effect of Clavulanic Acid on the In Vitro Synergism Between Carbenicillin and Gentamicin Against Serratia marcescens

Clavulanic acid, a potent β-lactamase inhibitor, reduced the minimum inhibitory concentrations of carbenicillin for 13 of 15 clinical isolates of Serratia marcescens by at least eightfold. The combination of clavulanic acid and carbenicillin also exhibited synergistic activity with gentamicin agains...

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Bibliographic Details
Main Authors: Sirisanthana, Thira, Lerner, Stephen A.
Format: Artigo
Language:Inglês
Published: 1979
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC352723/
https://ncbi.nlm.nih.gov/pubmed/380465
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