Modification of the Colorimetric Assay for Chloramphenicol in the Presence of Bilirubin

We recently found that bilirubin interferes with the colorimetric chloramphenicol assay of Kakemi et al. (K. T. Kakemi, T. Arita, and S. Ohashi, Yakugaku Zasshi 82:342–345, 1962). Levels of serum bilirubin alone (4 to 6 mg/dl) resulted in apparent concentrations of chloramphenicol which appear to be...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Mason, Edward O., Kaplan, Sheldon L., Baker, Carol J., Ritter, Dorothy A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1979
Materias:	Pharmacology and Therapeutics
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/464585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.4.544
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