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Neurotransmitter Release at the Thalamocortical Synapse Instructs Barrel Formation But Not Axon Patterning in the Somatosensory Cortex

To assess the impact of synaptic neurotransmitter release on neural circuit development, we analyzed barrel cortex formation after thalamic or cortical ablation of RIM1 and RIM2 proteins, which control synaptic vesicle fusion. Thalamus-specific deletion of RIMs reduced neurotransmission efficacy by...

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Detalhes bibliográficos
Main Authors: Narboux-Nême, Nicolas, Evrard, Alexis, Ferezou, Isabelle, Erzurumlu, Reha S., Kaeser, Pascal S., Lainé, Jeanne, Rossier, Jean, Ropert, Nicole, Südhof, Thomas C., Gaspar, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526954/
https://ncbi.nlm.nih.gov/pubmed/22553025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0343-12.2012
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