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Fascin1 Promotes Cell Migration of Mature Dendritic Cells

Dendritic cells (DCs) play central roles in innate and adaptive immunity. Upon maturation, DCs assemble numerous veil-like membrane protrusions, disassemble podosomes, and travel from the peripheral tissues to lymph nodes to present antigens to T-cells. These alterations in morphology and motility a...

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Bibliographic Details
Main Authors: Yamakita, Yoshihiko, Matsumura, Fumio, Lipscomb, Michael W., Chou, Po-chien, Werlen, Guy, Burkhardt, Janis K., Yamashiro, Shigeko
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526951/
https://ncbi.nlm.nih.gov/pubmed/21263068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001667
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