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Mechano-sensitivity of cardiac pacemaker function: Pathophysiological relevance, experimental implications, and conceptual integration with other mechanisms of rhythmicity
Cardiac pacemaker cells exhibit spontaneous, rhythmic electrical excitation, termed automaticity. This automatic initiation of action potentials requires spontaneous diastolic depolarisation, whose rate determines normal rhythm generation in the heart. Pacemaker mechanisms have been split recently i...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Pergamon Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526794/ https://ncbi.nlm.nih.gov/pubmed/23046620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2012.08.008 |
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