Highly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications

The next-generation ophthalmic anti-VEGF therapeutics must aim at being superior to the currently available agents with regard to potency and improved drug delivery, while still being stable and safe to use at elevated concentrations. We show here the generation of a set of highly potent VEGF-A anta...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stahl, Andreas, Stumpp, Michael T., Schlegel, Anja, Ekawardhani, Savira, Lehrling, Christina, Martin, Gottfried, Gulotti-Georgieva, Maya, Villemagne, Denis, Forrer, Patrik, Agostini, Hansjürgen T., Binz, H. Kaspar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Netherlands 2012
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526737/
https://ncbi.nlm.nih.gov/pubmed/22983424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9302-0
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