Dengue Viral RNA Levels in Peripheral Blood Mononuclear Cells Are Associated with Disease Severity and Preexisting Dengue Immune Status

BACKGROUND: Infection with dengue viruses (DENV) causes a wide range of manifestations from asymptomatic infection to a febrile illness called dengue fever (DF), to dengue hemorrhagic fever (DHF). The in vivo targets of DENV and the relation between the viral burden in these cells and disease severi...

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Hauptverfasser: Srikiatkhachorn, Anon, Wichit, Sineewanlaya, Gibbons, Robert V., Green, Sharone, Libraty, Daniel H., Endy, Timothy P., Ennis, Francis A., Kalayanarooj, Siripen, Rothman, Alan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526575/
https://ncbi.nlm.nih.gov/pubmed/23284680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051335
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