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Exon capture and bulk segregant analysis: rapid discovery of causative mutations using high-throughput sequencing
BACKGROUND: Exome sequencing has transformed human genetic analysis and may do the same for other vertebrate model systems. However, a major challenge is sifting through the large number of sequence variants to identify the causative mutation for a given phenotype. In models like Xenopus tropicalis,...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526394/ https://ncbi.nlm.nih.gov/pubmed/23171430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-649 |
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