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Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors

Natural killer cell (NK cell)–based immunotherapy of cancer is hampered by the transient effector function of NK cells. Recently, mouse IL-12/15/18–preactivated NK cells were shown to persist with sustained effector function in vivo. Our study investigated the antitumor activity of such NK cells. A...

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Autors principals: Ni, Jing, Miller, Matthias, Stojanovic, Ana, Garbi, Natalio, Cerwenka, Adelheid
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526364/
https://ncbi.nlm.nih.gov/pubmed/23209317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120944
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