Therapeutic Effects of PPARα Agonists on Diabetic Retinopathy in Type 1 Diabetes Models

Retinal vascular leakage, inflammation, and neovascularization (NV) are features of diabetic retinopathy (DR). Fenofibrate, a peroxisome proliferator–activated receptor α (PPARα) agonist, has shown robust protective effects against DR in type 2 diabetic patients, but its effects on DR in type 1 diab...

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Bibliographic Details
Main Authors: Chen, Ying, Hu, Yang, Lin, Mingkai, Jenkins, Alicia J., Keech, Anthony C., Mott, Robert, Lyons, Timothy J., Ma, Jian-xing
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2013
Subjects:
Complications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526044/
https://ncbi.nlm.nih.gov/pubmed/23043158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0413
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