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Hyperglycemia Slows Embryonic Growth and Suppresses Cell Cycle via Cyclin D1 and p21

In pregnant women, the diabetic condition results in a three- to fivefold increased risk for fetal cardiac malformations as a result of elevated glucose concentrations and the resultant osmotic stress in the developing embryo and fetus. Heart development before septation in the chick embryo was stud...

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Detalhes bibliográficos
Main Authors: Scott-Drechsel, Devon E., Rugonyi, Sandra, Marks, Daniel L., Thornburg, Kent L., Hinds, Monica T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526024/
https://ncbi.nlm.nih.gov/pubmed/23193186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0161
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