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Loss of RAB-3/A in C. elegans and the mouse affects behavioral response to ethanol

The mechanisms by which ethanol induces changes in behavior are not well understood. Here we show that C. elegans loss-of-function mutations in the synaptic vesicle-associated RAB-3 protein and its GTP exchange factor AEX-3 confer resistance to the acute locomotor effects of ethanol. Similarly, mice...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kapfhamer, David, Bettinger, Jill C., Davies, Andrew G., Eastman, Catharine L., Smail, Emily A., Heberlein, Ulrike, McIntire, Steven L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526002/
https://ncbi.nlm.nih.gov/pubmed/18397381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2008.00404.x
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