लोड हो रहा है...
Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe
Human serum transferrin (hTF) binds Fe(III) tightly but reversibly, and delivers it to cells via a receptor-mediated endocytosis process. The metal-binding and release result in significant conformational changes of the protein. Here, we report the crystal structures of diferric-hTF (Fe(N)Fe(C)-hTF)...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525939/ https://ncbi.nlm.nih.gov/pubmed/23256035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00999 |
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