Integrating Comparative Effectiveness Design Elements and Endpoints Into a Phase III, Randomized Clinical Trial (SWOG S1007) Evaluating OncotypeDX-Guided Management for Women With Breast Cancer Involving Lymph Nodes

Women with breast cancer involving the lymph nodes are typically treated with cytotoxic chemotherapy. Retrospective evaluations of prior studies suggest that the 21-gene test (OncotypeDX®), may allow identification of those who can safely avoid chemotherapy. To better understand the performance of t...

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Main Authors: Ramsey, Scott D., Barlow, William E., Gonzalez-Angulo, Ana M., Tunis, Sean, Baker, Laurence, Crowley, John, Deverka, Patricia, Veenstra, David, Hortobagyi, Gabriel N.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525786/
https://ncbi.nlm.nih.gov/pubmed/23000081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2012.09.003
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