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Cholinergic blockade frees fear extinction from its contextual dependency

BACKGROUND: Fears that are maladaptive or inappropriate can be reduced through extinction training. However, extinction is highly context-sensitive, resulting in the renewal of fear following shifts in context, and limiting the clinical efficacy of extinction training. Lesion and inactivation studie...

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Detalhes bibliográficos
Main Authors: Zelikowsky, Moriel, Hast, Timothy A., Bennett, Rebecca Z., Merjanian, Michael, Nocera, Nathaniel A., Ponnusamy, Ravikumar, Fanselow, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525775/
https://ncbi.nlm.nih.gov/pubmed/22981655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.08.006
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