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Amikacin Assay in Serum by High-Performance Liquid Chromatography

A high-performance liquid chromatographic method for the quantitative determination of amikacin in serum is described. The antibiotic was separated from serum by adsorption on silica gel. The adsorbed drug was then derivatized with o-phthalaldehyde and eluted with ethanol. The derivatized amikacin w...

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Detalhes bibliográficos
Main Authors: Maitra, Shyamal K., Yoshikawa, Thomas T., Steyn, Catherine M., Guze, Lucien B., Schotz, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC352573/
https://ncbi.nlm.nih.gov/pubmed/369456
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