Metformin Alters The Insulin Signaling Pathway In Ischemic Cardiac Tissue In A Swine Model Of Metabolic Syndrome

OBJECTIVE: The purpose of this study is to evaluate the effect of metformin on insulin signaling in ischemic cardiac tissue in a swine model of metabolic syndrome. METHODS: Ossabaw miniswine were fed either a regular diet (OC) or a hypercaloric diet (OHC, OHCM). After nine weeks, all animals underwe...

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Main Authors: Elmadhun, Nassrene Y., Lassaletta, Antonio D., Chu, Louis. M., Sellke, Frank W.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525723/
https://ncbi.nlm.nih.gov/pubmed/23083540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2012.09.028
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