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BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells

Neurons resembling the spiral ganglion neurons (SGNs) of the auditory nerve can be generated from embryonic stem cells through induced over-expression of the transcription factor Neurogenin-1 (Neurog1). While recapitulating this developmental pathway produces glutamatergic, bipolar neurons reminisce...

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Detalles Bibliográficos
Autores principales: Purcell, Erin K., Yang, Amy, Liu, Liqian, Velkey, J. Matthew, Morales, Marti M., Duncan, R. Keith
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525722/
https://ncbi.nlm.nih.gov/pubmed/23089626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2012.08.005
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