UK-18,892: Resistance to Modification by Aminoglycoside-Inactivating Enzymes

UK-18,892, a new semisynthetic aminoglycoside, was active against bacteria possessing aminoglycoside-inactivating enzymes, with the exception of some known to possess AAC(6′) or AAD(4′) enzymes. This activity has been rationalized by using cell-free extracts of bacteria containing known inactivating...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Andrews, R. J., Brammer, K. W., Cheeseman, H. E., Jevons, S.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1978
Materias:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/742872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.6.846
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