Dexamethasone Reduces Sensitivity to Cisplatin by Blunting p53-Dependent Cellular Senescence in Non-Small Cell Lung Cancer

INTRODUCTION: Dexamethasone (DEX) co-treatment has proved beneficial in NSCLC patients, improving clinical symptoms by the reduction of side effects after chemotherapy. However, recent studies have shown that DEX could render cancer cells more insensitive to cytotoxic drug therapy, but it is not kno...

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Detalhes bibliográficos
Main Authors: Ge, Haiyan, Ni, Songshi, Wang, Xingan, Xu, Nuo, Liu, Ying, Wang, Xun, Wang, Lingyan, Song, Dongli, Song, Yuanlin, Bai, Chunxue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525662/
https://ncbi.nlm.nih.gov/pubmed/23272171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051821
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