Cardiotrophin-1 determines liver engraftment of syngenic colon carcinoma cells through an immune system-mediated mechanism

Cardiotrophin-1 (CT-1/CTF1) is a member of the interleukin-6 (IL-6) family of cytokines that stimulates STAT-3 phosphorylation in cells bearing the cognate receptor. We report that Ctf1(−/−) mice (hereby referred to as CT-1(−/−) mice) are resistant to the hepatic engraftment of MC38 colon carcinoma...

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Main Authors: Bustos, Matilde, Dubrot, Juan, Martinez-Anso, Eduardo, Larequi, Eduardo, Castaño, David, Palazon, Asis, Belza, Idoia, Sanmamed, Miguel F., Perez-Gracia, Jose Luis, Ortiz de Solorzano, Carlos, alfaro, Carlos, Melero, Ignacio
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525608/
https://ncbi.nlm.nih.gov/pubmed/23264899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22504
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