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Activity of Derivatives and Analogs of Dapsone Against Mycobacterium leprae

Of 25 dapsone derivatives and analogs screened for activity against Mycobacterium leprae in the mouse footpad system, only 7 were active. All seven were metabolized to or contaminated with dapsone.

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Author: Levy, Louis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1978
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/727767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.5.791
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