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Clavulanic Acid, a Novel Inhibitor of β-Lactamases

Clavulanic acid, Z-(2R,5R)-3-(β-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0] heptane-2-carboxylic acid, has been shown to be an effective inhibitor of the β-lactamases of the Richmond types II, III, IV, and V. Inhibition is a time-dependent reaction and is irreversible. Clavulanic acid had po...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Neu, Harold C., Fu, Kwung P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/310279/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.5.650
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