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Neurofibromatosis type 1-associated tumours: Their somatic mutational spectrum and pathogenesis
Somatic gene mutations constitute key events in the malignant transformation of human cells. Somatic mutation can either actively speed up the growth of tumour cells or relax the growth constraints normally imposed upon them, thereby conferring a selective (proliferative) advantage at the cellular l...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525246/ https://ncbi.nlm.nih.gov/pubmed/22155606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-5-6-623 |
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