New Antipseudomonal Penicillin, PC-904: Affinity to Penicillin-Binding Proteins and Inhibition of the Enzyme Cross-Linking Peptidoglycan

The mechanism of action of a new antipseudomonal penicillin, PC-904, was studied with respect to its binding affinities to penicillin-binding proteins (PBPs) and its inhibitory activities on cross-linking enzymes of peptidoglycan synthesis in vitro. PC-904 showed especially high affinity (compared w...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Noguchi, Hiroshi, Matsuhashi, Michio, Takaoka, Masayoshi, Mitsuhashi, Susumu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1978
Assuntos:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/102247/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.4.617
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