Prediction of Cefazolin Penetration into High- and Low-Protein-Containing Extravascular Fluid: New Method for Performing Simultaneous Studies

The effect of extravascular fluid protein concentration and drug-protein binding was studied in rabbits with subcutaneously implanted Visking chambers. Chambers containing serum or saline were simultaneously studied in three animals by injecting cefazolin (30 mg/kg) intramuscularly every 4 h for fou...

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Detaylı Bibliyografya

Yayımlandı:	Antimicrob Agents Chemother
Asıl Yazarlar:	Peterson, Lance R., Gerding, Dale N.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1978
Konular:	Pharmacology and Therapeutics
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/718152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.4.533
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