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A machine learning approach to predicting protein-ligand binding affinity with applications to molecular docking

MOTIVATION: Accurately predicting the binding affinities of large sets of diverse protein-ligand complexes is an extremely challenging task. The scoring functions that attempt such computational prediction are essential for analysing the outputs of Molecular Docking, which is in turn an important te...

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Detalhes bibliográficos
Main Authors: Ballester, Pedro J., Mitchell, John B.O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524828/
https://ncbi.nlm.nih.gov/pubmed/20236947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq112
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