CP-45,899, a Beta-Lactamase Inhibitor That Extends the Antibacterial Spectrum of Beta-Lactams: Initial Bacteriological Characterization

CP-45,899 {3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 4,4-dioxide, [2S-(2α,5α)]} is an irreversible inhibitor of several bacterial penicillinases and cephalosporinases. In the presence of low concentrations of CP-45,899, ampicillin and other β-lactams readily inhibit the...

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Bibliografiset tiedot

Julkaisussa:	Antimicrob Agents Chemother
Päätekijät:	English, Arthur R., Retsema, James A., Girard, Arthur E., Lynch, John E., Barth, Wayne E.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1978
Aiheet:	Physiological Effects and Microbial Susceptibility
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/309306/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.3.414
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