CP-45,899, a Beta-Lactamase Inhibitor That Extends the Antibacterial Spectrum of Beta-Lactams: Initial Bacteriological Characterization

CP-45,899 {3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 4,4-dioxide, [2S-(2α,5α)]} is an irreversible inhibitor of several bacterial penicillinases and cephalosporinases. In the presence of low concentrations of CP-45,899, ampicillin and other β-lactams readily inhibit the...

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Bibliografiska uppgifter
Huvudupphovsmän: English, Arthur R., Retsema, James A., Girard, Arthur E., Lynch, John E., Barth, Wayne E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1978
Ämnen:
Physiological Effects and Microbial Susceptibility
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC352474/
https://ncbi.nlm.nih.gov/pubmed/309306
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