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Beta-Lactamase Stability of HR 756, a Novel Cephalosporin, Compared to That of Cefuroxime and Cefoxitin

The stability to β-lactamase hydrolysis of HR 756, a new cephalosporin antibiotic, was compared to the β-lactamase stability of cefoxitin and cefuroxime. HR 756, cefoxitin, and cefuroxime were not hydrolyzed by Richmond type I, III, IV, and V β-lactamases. Antibacterial activity of HR 756 correlated...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Fu, Kwung P., Neu, Harold C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1978
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352458/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/101128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.3.322
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