Nanoparticles for Improved Local Retention after Intra-Articular Injection into the Knee Joint

PURPOSE: To evaluate using cationic polymeric nanoparticles that interact with hyaluronate to form ionically cross-linked hydrogels to increase the intra-articular retention time of osteoarthritis drugs in the synovial cavity. METHODS: In vitro tests included nanoparticle release from cross-linked h...

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Autors principals: Morgen, Michael, Tung, David, Boras, Britton, Miller, Warren, Malfait, Anne-Marie, Tortorella, Micky
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524502/
https://ncbi.nlm.nih.gov/pubmed/22996566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0870-x
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