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ERα Signaling Regulates MMP3 Expression to Induce FasL Cleavage and Osteoclast Apoptosis
The benefits of estrogens on bone health are well established; how estrogens signal to regulate bone formation and resorption is less well understood. We show here that 17β-estradiol (E2)-induced apoptosis of bone-resorbing osteoclasts is mediated by cleavage and solubilization of osteoblast-express...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524410/ https://ncbi.nlm.nih.gov/pubmed/22927007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1747 |
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