Antibiotic Biosynthesis by Cofermentation of Blocked Mutants of Two Micromonospora Species

Two aminocyclitol-negative Micromonospora mutants representing two different species, M. purpurea and M. inyoensis, and blocked at different steps in the biosynthetic pathway were paired and cofermented for the synthesis of antibiotics. The two blocked mutants were incapable of producing antibiotics...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Lee, B. K., Nagabhushan, T. L., Condon, R. G., Cooper, A. B., Waitz, J. A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1978
Soggetti:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352407/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/686710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.1.73
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