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IGF2/H19 hypomethylation is tissue, cell, and CpG site dependent and not correlated with body asymmetry in adolescents with Silver-Russell syndrome
BACKGROUND: Silver-Russell syndrome (SRS) is characterized by severe intrauterine and postnatal growth failure and frequent body asymmetry. Half of the patients with SRS carry a DNA hypomethylation of the imprinting center region 1 (ICR1) of the insulin-like growth factor 2 (IGF2)/H19 locus, and the...
में बचाया:
मुख्य लेखकों: | , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
BioMed Central
2012
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523983/ https://ncbi.nlm.nih.gov/pubmed/22989232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-4-15 |
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