Fas-Independent T-Cell Apoptosis by Dendritic Cells Controls Autoimmune Arthritis in MRL/lpr Mice

BACKGROUND: Although autoimmunity in MRL/lpr mice occurs due to a defect in Fas-mediated cell death of T cells, the role of Fas-independent apoptosis in pathogenesis has rarely been investigated. We have recently reported that receptor activator of nuclear factor (NF)-κB ligand (RANKL)-activated den...

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Hauptverfasser: Izawa, Takashi, Kondo, Tomoyuki, Kurosawa, Mie, Oura, Ritsuko, Matsumoto, Kazuma, Tanaka, Eiji, Yamada, Akiko, Arakaki, Rieko, Kudo, Yasusei, Hayashi, Yoshio, Ishimaru, Naozumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523790/
https://ncbi.nlm.nih.gov/pubmed/23300516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048798
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