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The crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata

The saliva of blood-feeding parasites is a rich source of peptidase inhibitors that help overcome the host’s defense during host-parasite interactions. Using proteomic analysis, the cystatin OmC2 was demonstrated in the saliva of the soft tick Ornithodoros moubata, an important disease-vector transm...

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Detalhes bibliográficos
Main Authors: Salát, Jiří, Paesen, Guido C., Řezáčová, Pavlína, Kotsyfakis, Michalis, Kovářová, Zuzana, Šanda, Miloslav, Majtán, Juraj, Grunclová, Lenka, Horká, Helena, Andersen, John F., Brynda, Jiří, Horn, Martin, Nunn, Miles A., Kopáček, Petr, Kopecký, Jan, Mareš, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523712/
https://ncbi.nlm.nih.gov/pubmed/20545626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100280
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