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Effect of lithium chloride and antineoplastic drugs on survival and cell cycle of androgen-dependent prostate cancer LNCap cells

OBJECTIVE: Glycogen synthase kinase-3β (GSK-3β) has been reported to be required for androgen receptor (AR) activity. This study sought to determine the usefulness of lithium chloride (LiCl) as a highly selective inhibitor of GSK-3β to increase the sensitivity of LNCap cells to doxorubicin (Dox), et...

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Bibliografski detalji
Glavni autori: Azimian-Zavareh, Vajihe, Hossein, Ghamartaj, Janzamin, Ehsan
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523498/
https://ncbi.nlm.nih.gov/pubmed/23248400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.103265
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