Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ([Image: see text])

Peroxisome proliferator-activated receptor gamma (PPARγ) agonists are used for the treatment of type 2 diabetes and metabolic syndrome. However, the currently used PPARγ agonists display serious side effects, which has led to a great interest in the discovery of novel ligands with favorable properti...

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Detalhes bibliográficos
Main Authors: Fakhrudin, Nanang, Ladurner, Angela, Atanasov, Atanas G., Heiss, Elke H., Baumgartner, Lisa, Markt, Patrick, Schuster, Daniela, Ellmerer, Ernst P., Wolber, Gerhard, Rollinger, Judith M., Stuppner, Hermann, Dirsch, Verena M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523390/
https://ncbi.nlm.nih.gov/pubmed/20064974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.062141
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