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The individual survival benefits of tumor necrosis factor soluble receptor and fluid administration are not additive in a rat sepsis model
BACKGROUND: Tumor necrosis factor (TNF) antagonists [e.g., TNF soluble receptor (TNFsr)] improved survival in preclinical but not clinical sepsis trials. However fluid support—itself beneficial—is standard clinically but rarely employed in pre-clinical sepsis models. We hypothesized that these thera...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523295/ https://ncbi.nlm.nih.gov/pubmed/21922303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-011-2324-z |
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