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Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood

Cdc42 regulates the initial establishment of cytoskeletal and junctional structures, but only little is known about its role at later stages of cellular differentiation. We studied Cdc42′s role in vivo in auditory supporting cells, epithelial cells with high structural complexity. Cdc42 inactivation...

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Detalhes bibliográficos
Main Authors: Anttonen, Tommi, Kirjavainen, Anna, Belevich, Ilya, Laos, Maarja, Richardson, William D., Jokitalo, Eija, Brakebusch, Cord, Pirvola, Ulla
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523287/
https://ncbi.nlm.nih.gov/pubmed/23248743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00978
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