A Dominant EV71-Specific CD4+ T Cell Epitope Is Highly Conserved among Human Enteroviruses

CD4+ T cell-mediated immunity plays a central role in determining the immunopathogenesis of viral infections. However, the role of CD4+ T cells in EV71 infection, which causes hand, foot and mouth disease (HFMD), has yet to be elucidated. We applied a sophisticated method to identify promiscuous CD4...

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Detalhes bibliográficos
Main Authors: Wei, Ruicheng, Yang, Chunfu, Zeng, Mei, Terry, Frances, Zhu, Kai, Yang, Chunhui, Altmeyer, Ralf, Martin, William, De Groot, Anne S., Leng, Qibin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522610/
https://ncbi.nlm.nih.gov/pubmed/23251663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051957
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