Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection

BACKGROUND: Salvinorin A (SA), the main active component of Salvia Divinorum, is a non-nitrogenous kappa opioid receptor (KOR) agonist. It has been shown to reduce acute pain and to exert potent antinflammatory effects. This study assesses the effects and the mode of action of SA on formalin-induced...

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Detalhes bibliográficos
Main Authors: Guida, Francesca, Luongo, Livio, Aviello, Gabriella, Palazzo, Enza, De Chiaro, Maria, Gatta, Luisa, Boccella, Serena, Marabese, Ida, Zjawiony, Jordan K, Capasso, Raffaele, Izzo, Angelo A, de Novellis, Vito, Maione, Sabatino
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522567/
https://ncbi.nlm.nih.gov/pubmed/22913292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-60
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