Identification of sites in apolipoprotein A-I susceptible to chymase and carboxypeptidase A digestion

MCs (mast cells) adversely affect atherosclerosis by promoting the progression of lesions and plaque destabilization. MC chymase cleaves apoA-I (apolipoprotein A-I), the main protein component of HDL (high-density lipoprotein). We previously showed that C-terminally truncated apoA-I (cleaved at the...

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Détails bibliographiques
Auteurs principaux: Usami, Yoko, Kobayashi, Yukihiro, Kameda, Takahiro, Miyazaki, Akari, Matsuda, Kazuyuki, Sugano, Mitsutoshi, Kawasaki, Kenji, Kurihara, Yuriko, Kasama, Takeshi, Tozuka, Minoru
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2012
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Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522476/
https://ncbi.nlm.nih.gov/pubmed/23072735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20120094
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