Comparative distribution of gentamicin, tobramycin, sisomicin, netilmicin, and amikacin in interstitial fluid in rabbits.

We compared the penetration of five aminoglycosides into interstitial fluid (IF). IF was obtained in rabbits from Silastic tissue cages. Intramuscular injections were made: 1.5 mg/kg per dose for gentamicin (G), tobramycin (T), sisomicin (S), and netilmicin (N) and 7.5 mg/kg per dose for amikacin (A...

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Bibliographic Details
Main Authors: Carbon, C, Contrepois, A, Lamotte-Barrillon, S
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC352247/
https://ncbi.nlm.nih.gov/pubmed/263882
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