Proteolytic Processing of Connective Tissue Growth Factor in Normal Ocular Tissues and during Corneal Wound Healing

PURPOSE. Connective tissue growth factor (CTGF) is a fibrogenic cytokine that is up-regulated by TGF-β and mediates most key fibrotic actions of TGF-β, including stimulation of synthesis of extracellular matrix and differentiation of fibroblasts into myofibroblasts. This study addresses the role of...

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Bibliografiske detaljer
Main Authors: Robinson, Paulette M., Smith, Tyler S., Patel, Dilan, Dave, Meera, Lewin, Alfred S., Pi, Liya, Scott, Edward W., Tuli, Sonal S., Schultz, Gregory S.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2012
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522436/
https://ncbi.nlm.nih.gov/pubmed/23139278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10419
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