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Inhibition of sperm capacitation and fertilizing capacity by adjudin is mediated by chloride and its channels in humans

STUDY QUESTION: Does adjudin disrupt chloride ion (Cl(−)) ion transport function in human sperm and impede sperm capacitation and fertilizing ability in vitro? SUMMARY ANSWER: In this study the results indicate that adjudin is a potent blocker of Cl(−) channels: disrupting Cl(−) ion transport functi...

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Hlavní autoři: Li, Kun, Ni, Ya, He, Yi, Chen, Wen-Ying, Lu, Jian-Xin, Cheng, C. Yan, Ge, Ren-Shan, Shi, Qi-Xian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522416/
https://ncbi.nlm.nih.gov/pubmed/23117128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/des384
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