Characterization of a Flavoprotein Oxidase from Opium Poppy Catalyzing the Final Steps in Sanguinarine and Papaverine Biosynthesis

Benzylisoquinoline alkaloids are a diverse class of plant specialized metabolites that includes the analgesic morphine, the antimicrobials sanguinarine and berberine, and the vasodilator papaverine. The two-electron oxidation of dihydrosanguinarine catalyzed by dihydrobenzophenanthridine oxidase (DB...

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Bibliografiske detaljer
Main Authors: Hagel, Jillian M., Beaudoin, Guillaume A. W., Fossati, Elena, Ekins, Andrew, Martin, Vincent J. J., Facchini, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Plant Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522292/
https://ncbi.nlm.nih.gov/pubmed/23118227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420414
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