Reevaluation of the Mode of Action of Streptolydigin in Escherichia coli: Induction of Transcription Termination In Vivo

Growth of the permeable strain AS19 of Escherichia coli B is more sensitive to the antibiotic streptolydigin than is in vitro ribonucleic acid (RNA) synthesis. The in vivo chain elongation rates of lacZ messenger RNA and ribosomal RNA are not affected at 1.5 × 10(−6) M, a concentration that reduces...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Meyenburg, Kaspar Von, Nielsen, Lissie Dahlgren, Johnsen, Knud, Molin, Søren, Svenningsen, Bo, Miozzari, Guiseppe
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1978
Schlagworte:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/348095/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.2.234
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